{"id":162,"date":"2025-11-20T07:26:04","date_gmt":"2025-11-19T22:26:04","guid":{"rendered":"https:\/\/synapseconferencenet.com\/?p=162"},"modified":"2025-11-20T07:26:39","modified_gmt":"2025-11-19T22:26:39","slug":"%e5%96%98%e6%81%af","status":"publish","type":"post","link":"https:\/\/synapseconferencenet.com\/?p=162","title":{"rendered":"\u5598\u606f"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">\u3010\u75c5\u614b\u3011<\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"http:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/067e58ac-5d24-4f2b-985a-eb5601869c5f.png\" alt=\"\" class=\"wp-image-163\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/067e58ac-5d24-4f2b-985a-eb5601869c5f.png 1536w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/067e58ac-5d24-4f2b-985a-eb5601869c5f-300x200.png 300w\" sizes=\"auto, (max-width: 1536px) 100vw, 1536px\" \/><\/figure>\n\n\n\n<p>\u56f3:\u53c2\u8003\u6587\u732e1\u3088\u308a\u5f15\u7528\u3000\u4e00\u90e8\u6539\u5909<\/p>\n\n\n\n<p>&lt;2\u578b\u708e\u75c7&gt;:Th2\u3084ILC2(2\u578b\u81ea\u7136\u30ea\u30f3\u30d1\u7403)\u304c\u95a2\u4e0e\u3059\u308b\u5598\u606f<\/p>\n\n\n\n<p>1,\u5438\u5165\u611f\u4f5c\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8, \u6a39\u72b6\u7d30\u80de\u306a\u3069\u306e\u6297\u539f\u63d0\u793a\u7d30\u80de\u304c\u8caa\u98df<br>\u2192IL-4\u306a\u3069\u306e\u4f5c\u7528\u306b\u3088\u308a\u6297\u539f\u306b\u7279\u7570\u7684\u306a\u53d7\u5bb9\u4f53\u3092\u6301\u3064Th2\u7d30\u80de\u306b\u5206\u5316<br>\u2192Th2\u7d30\u80de\u304cIL-4,5,9,13\u306a\u3069\u3092\u7523\u751f<\/p>\n\n\n\n<p>\u30fbIL-4,13:<br>\u3000\u30fbB\u7d30\u80de\u306e\u30af\u30e9\u30b9\u30b9\u30a4\u30c3\u30c1\u3092\u8a98\u5c0e\u3057, IgE\u7523\u751f\u3092\u4fc3\u9032<br>\u3000\u2192IgE\u306f\u80a5\u6e80\u7d30\u80de\u3084\u597d\u5869\u57fa\u7403\u306e\u8868\u9762\u306eFc\u03b5RI\u306b\u7d50\u5408\u3057, \u8131\u9846\u7c92\u3092\u4fc3\u3059<br>\u3000\u2192\u30d2\u30b9\u30bf\u30df\u30f3\u3084\u30ed\u30a4\u30b3\u30c8\u30ea\u30a8\u30f3\u306a\u3069\u306e\u708e\u75c7\u6027\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u3092\u653e\u51fa\u3057, \u5373\u6642\u578b\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3092\u8d77\u3053\u3059<br>\u3000\u30fb\u6c17\u9053\u4e0a\u76ae\u306b\u4f5c\u7528\u3059\u308b\u3068STAT6\u3092\u4ecb\u3057\u3066L-\u30a2\u30eb\u30ae\u30cb\u30f3\u304b\u3089\u4e00\u9178\u5316\u7a92\u7d20\u304c\u5408\u6210\u3055\u308c\u308b<br>\u3000\u2192\u547c\u6c17\u4e2d\u306bNO\u304c\u653e\u51fa\u3055\u308c\u308b<\/p>\n\n\n\n<p>\u30fbIL-5:\u597d\u9178\u7403\u306e\u6d3b\u6027\u5316\u3084\u751f\u5b58\u3092\u5ef6\u9577\u3059\u308b<\/p>\n\n\n\n<p>\u30fbIL-13:\u6c17\u9053\u4e0a\u76ae\u306e\u676f\u7d30\u80de\u5316\u751f, \u7c98\u6db2\u7523\u751f\u4ea2\u9032\u3084\u5e73\u6ed1\u7b4b\u53ce\u7e2e, \u6c17\u9053\u306e\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u3092\u4fc3\u9032\u3059\u308b<\/p>\n\n\n\n<p>2,\u74b0\u5883\u8981\u56e0(\u611f\u67d3\u3084\u5927\u6c17\u6c5a\u67d3\u306a\u3069)\u306b\u3088\u308a\u6c17\u9053\u4e0a\u76ae\u7d30\u80de\u304b\u3089IL-33, TSLP, IL-25\u306a\u3069\u306e\u4e0a\u76ae\u7531\u6765\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u7523\u751f<br>\u2192ILC2\u304c\u6d3b\u6027\u5316\u3057, IL-5, 13\u3092\u7523\u751f\u3055\u305b\u6c17\u9053\u708e\u75c7\u3092\u60f9\u8d77\u3059\u308b<\/p>\n\n\n\n<p>&lt;T2-low\u5598\u606f&gt;:\u597d\u4e2d\u7403\u6027\u3068\u597d\u9178\u7403\u6027\u306e\u95a2\u4e0e\u304c\u8a00\u308f\u308c\u3066\u3044\u308b<\/p>\n\n\n\n<p>1,\u6c17\u9053\u4e0a\u76ae\u306bIL-17\u304c\u4f5c\u7528\u3059\u308b+\u30a8\u30f3\u30c9\u30c8\u30ad\u30b7\u30f3\u306a\u3069\u306e\u523a\u6fc0\u3067IL-8\u304c\u7523\u751f\u3055\u308c\u308b<br>\u2192IL-8\u306f\u597d\u4e2d\u7403\u3092\u8a98\u5c0e\u3059\u308b<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u3010\u77e5\u8b58\u3011<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\uff12\u578b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u95a2\u4e0e\u304c\u3042\u308b\u5598\u606f\u3092T2-high\u5598\u606f\u3068\u547c\u3076<br>*\uff12\u578b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u95a2\u4e0e\u304c\u4e4f\u3057\u3044\u3068\u8003\u3048\u3089\u308c\u308b\u5598\u606f\u3092T2-low\u5598\u606f\u3068\u547c\u3076<\/li>\n\n\n\n<li>T2-high\u5598\u606f\u304c\u534a\u6570\u4ee5\u4e0a<\/li>\n\n\n\n<li>T2-low\u5598\u606f\u306f10-20%\u5b58\u5728\u3057, \u30b9\u30c6\u30ed\u30a4\u30c9\u53cd\u5fdc\u6027\u304c\u60aa\u304f\u6cbb\u7642\u306b\u96e3\u6e0b\u3057\u3084\u3059\u3044<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">\u3010\u96e3\u6cbb\u5316\u8981\u56e0\u3011<\/h3>\n\n\n\n<p>&lt;\u4e0a\u6c17\u9053\u306e\u597d\u9178\u7403\u6027\u708e\u75c7&gt;<\/p>\n\n\n\n<p>\u4e0a\u6c17\u9053, \u4e0b\u6c17\u9053\u306f\u89e3\u5256\u5b66\u7684\u306b\u9023\u7d9a\u6027\u3067\u3042\u308a, \u4e2d\u8033\u306f\u9f3b\u7c98\u819c\u3084\u6c17\u9053\u3068\u540c\u3058\u7d44\u7e54\u5b66\u7684\u306b\u591a\u5217\u7e4a\u6bdb\u4e0a\u76ae\u3067\u3042\u308b\u3002<\/p>\n\n\n\n<p>\u2192\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e, \u597d\u9178\u7403\u6027\u526f\u9f3b\u8154\u708e, \u597d\u9178\u7403\u6027\u4e2d\u8033\u708e\u306e\u5408\u4f75\u306f\u91cd\u75c7\u5316\u306e\u8981\u56e0\u306b\u306a\u308b<\/p>\n\n\n\n<p>1, \u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e<\/p>\n\n\n\n<p>\u30fb\u5c0f\u5150\u671f\u306b\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u304c\u3042\u308b\u3068\u5598\u606f\u306e\u767a\u75c7\u7387\u306f\uff13\u500d<\/p>\n\n\n\n<p>\u30fb\u5408\u4f75\u60a3\u8005\u306f\u767a\u4f5c\u56de\u6570\u304c\u591a\u304f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u4e0d\u826f\u306b\u306a\u308a\u3084\u3059\u3044<\/p>\n\n\n\n<p>*\u7279\u306b\u82b1\u7c89\u306e\u98db\u6563\u6642\u671f\u306f\u5897\u60aa\u3057\u3084\u3059\u3044<\/p>\n\n\n\n<p>2, \u597d\u9178\u7403\u6027\u526f\u9f3b\u8154\u708e<\/p>\n\n\n\n<p>\u30fb\u6162\u6027\u526f\u9f3b\u8154\u708e\u306f\u5598\u606f\u5897\u60aa\u306e\u30ea\u30b9\u30af\u56e0\u5b50<\/p>\n\n\n\n<p>\u30fb\u975e\u597d\u9178\u7403\u6027\u526f\u9f3b\u8154\u708e\u3068\u6bd4\u8f03\u3057\u3066\u55c5\u899a\u969c\u5bb3\u304c\u5f37\u304f, \u7be9\u9aa8\u6d1e\u512a\u4f4d<\/p>\n\n\n\n<p>3, \u597d\u9178\u7403\u6027\u4e2d\u8033\u708e<\/p>\n\n\n\n<p>\u30fb\u5598\u606f\u3084\u526f\u9f3b\u8154\u708e\u306b\u5148\u884c\u3057\u3066\u767a\u75c7\u3059\u308b<\/p>\n\n\n\n<p>\u30fb\u30cb\u30ab\u30ef\u72b6\u306e\u8033\u6f0f\u304c\u7279\u5fb4<\/p>\n\n\n\n<p>\u30fb\u672b\u68a2\u597d\u9178\u7403\u6570\u304c\u9ad8\u304f, \u6c17\u9053\u58c1\u306e\u80a5\u539a\u3092\u8a8d\u3081, 1\u79d2\u7387\u306e\u4f4e\u4e0b\u304c\u307f\u3089\u308c\u3084\u3059\u3044<\/p>\n\n\n\n<p>&lt;\u80a5\u6e80&gt;<\/p>\n\n\n\n<p>\u30fb\u5598\u606f\u306e\u5897\u60aa\u56e0\u5b50\u3067\u3042\u308a, ICS\u306e\u6cbb\u7642\u53cd\u5fdc\u6027\u3082\u4f4e\u3044<\/p>\n\n\n\n<p>\u2192\u6297\u30ed\u30a4\u30b3\u30c8\u30ea\u30a8\u30f3\u85ac\u3084\u6297\u30b3\u30ea\u30f3\u85ac\u3092\u4f75\u7528\u3059\u308b<\/p>\n\n\n\n<p>\u30fb\u8179\u8154\u5185\u306e\u8102\u80aa\u6c88\u7740\u306b\u3088\u308b\u6a2a\u9694\u819c\u6319\u4e0a\u3084\u6162\u6027\u708e\u75c7, \u8eab\u4f53\u6d3b\u52d5\u306e\u4f4e\u4e0b\u306a\u3069\u304c\u539f\u56e0<\/p>\n\n\n\n<p>\u6700\u8fd1, \u6c17\u9053\u4e0a\u76ae\u306eTSLP, IL33\u306e\u767a\u73fe\u4ea2\u9032\u304c\u3042\u308a, \u5598\u606f\u60aa\u5316\u306e\u4e00\u52a9\u3068\u3057\u3066\u8003\u3048\u3089\u308c\u3066\u3044\u308b<\/p>\n\n\n\n<p>&lt;\u6c17\u9053\u5206\u6ccc\u4ea2\u9032&gt;<\/p>\n\n\n\n<p>\u30fbIL-13\u306b\u3088\u308b\u676f\u7d30\u80de\u306e\u904e\u5f62\u6210\u306b\u3088\u308b\u30e0\u30c1\u30f3\u7523\u751f\u5897\u52a0<\/p>\n\n\n\n<p>+IL-5\u306b\u3088\u308b\u597d\u9178\u7403\u6027\u6c17\u9053\u708e\u75c7\u306b\u3088\u308b\u597d\u9178\u7403\u30da\u30eb\u30aa\u30ad\u30b7\u30c0\u30fc\u30bc\u306e\u653e\u51fa\u2192\u30e0\u30c1\u30f3\u7523\u751f\u4ea2\u9032<\/p>\n\n\n\n<p>\u2192\u7c98\u6db2\u6813\u75d9\u6027<\/p>\n\n\n\n<p>\u30fb\u5927\u91cf\u306e\u7c98\u8abf\u6027\u75f0\u304c\u672b\u68a2\u6c17\u9053\u3092\u9589\u585e\u3055\u305b\u7a92\u606f\u3057, \u5598\u606f\u6b7b\u306b\u81f3\u308b\u75c7\u4f8b\u304c\u3042\u308b<\/p>\n\n\n\n<p>\u30fb\u6301\u7d9a\u6027\u306e\u7c98\u8abf\u6027\u75f0\u306f\u6c17\u6d41\u5236\u9650\u3092\u3059\u308b\u3053\u3068\u304c\u591a\u304f, \u5897\u60aa\u56de\u6570\u304c\u591a\u304b\u3063\u305f<\/p>\n\n\n\n<p>\u30fb\u672b\u68a2\u8840\u597d\u9178\u7403\u6570\u304c\u9ad8\u304f, FeNO\u306e\u4e0a\u6607\u304c\u8457\u540d<\/p>\n\n\n\n<p>\u30fb\u7c98\u6db2\u30b9\u30b3\u30a2\u3067\u8a55\u4fa1\u3059\u308b<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"956\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-21-1024x956.png\" alt=\"\" class=\"wp-image-164\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-21-1024x956.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-21-300x280.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-21-768x717.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-21.png 1028w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u56f3:\u53c2\u8003\u6587\u732e2\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<p>\u30fb\u6297IL-4\u53d7\u5bb9\u4f53\u03b1\u6297\u4f53\u306eDupilumab\u306e\u6295\u4e0e\u3067\u7c98\u6db2\u6813\u304c\u6e1b\u5c11\u3057\u305f\u5831\u544a\u3042\u308a<br>\u3000*\u6297IL-5\u53d7\u5bb9\u4f53\u03b1\u6297\u4f53\u3084\u6297TSLP\u6297\u4f53\u3067\u3082\u6539\u5584\u306e\u5831\u544a\u3042\u308a<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u3010\u691c\u67fb\u3011<\/h3>\n\n\n\n<p>&lt;\u8840\u6db2\u691c\u67fb&gt;<\/p>\n\n\n\n<p>\u30fb\u597d\u9178\u7403\u6570<\/p>\n\n\n\n<p>\u9ad8\u5024\u306e\u5598\u606f\u3067\u306f\u91cd\u75c7\u5ea6\u304c\u9ad8\u304f, \u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u4e0d\u826f\u306e\u30ea\u30b9\u30af\u304c\u4e0a\u304c\u308b<\/p>\n\n\n\n<p>300\/\u03bcL\u4ee5\u4e0a\u3067\u306f\u5897\u60aa\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044<\/p>\n\n\n\n<p>\u91cd\u75c7\u5598\u606f\u306b\u304a\u3044\u3066, \u672b\u68a2\u597d\u9178\u7403\u6570\u304c\u9ad8\u3044\u3068IL-5\u3092\u6a19\u7684\u3068\u3057\u305f\u751f\u7269\u88fd\u5264\u304c\u6709\u7528\u306e\u53ef\u80fd\u6027\u304c\u3042\u308b<\/p>\n\n\n\n<p>\u30fb\u8840\u4e2dIgE<\/p>\n\n\n\n<p>\u30a2\u30c8\u30d4\u30fc\u6027\u5598\u606f\u306e\u6307\u6a19<\/p>\n\n\n\n<p>\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u3084\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3092\u5408\u4f75\u3057\u3066\u3044\u308b\u3068\u9ad8\u5024\u306b\u306a\u308b<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>&lt;\u547c\u6c17\u4e2d\u4e00\u9178\u5316\u7a92\u7d20\u6fc3\u5ea6\u6e2c\u5b9a(FeNO)&gt;<\/p>\n\n\n\n<p>T2-high\u5598\u606f\u306e\u6307\u6a19<\/p>\n\n\n\n<p>ICS\u672a\u6cbb\u7642\u60a3\u8005<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>22bbp\u4ee5\u4e0a<\/td><td>37bbp\u4ee5\u4e0a<\/td><\/tr><tr><td>\u5598\u606f\u306e\u53ef\u80fd\u6027\u3092\u8003\u616e<\/td><td>\u5598\u606f\u306e\u53ef\u80fd\u6027\u304c\u9ad8\u3044<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>\u547c\u5438\u6a5f\u80fd\u6539\u5584\u306b\u3088\u308aFeNO\u306f\u4f4e\u4e0b\u3059\u308b<\/p>\n\n\n\n<p>*\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e\u3084\u30a6\u30a4\u30eb\u30b9\u3067\u306f\u4e0a\u6607\u3059\u308b<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>&lt;\u30d4\u30fc\u30af\u30d5\u30ed\u30fc\u30e1\u30fc\u30bf\u30fc&gt;<\/p>\n\n\n\n<p>\u6700\u5927\u98a8\u901f\u3092\u6e2c\u5b9a\u3067\u304d\u308b<\/p>\n\n\n\n<p>\u5728\u5b85\u306a\u3069\u3067\u306e\u5598\u606f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306e\u6307\u6a19\u306b\u826f\u3044<\/p>\n\n\n\n<p>*\u5e02\u8ca9\u3067\u8cfc\u5165\u3067\u304d\u308b<\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1024\" src=\"http:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-22.png\" alt=\"\" class=\"wp-image-165\" style=\"width:202px;height:auto\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-22.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-22-300x300.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-22-150x150.png 150w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u65e5\u5185\u5909\u52d5\u309220\uff05\u4ee5\u5185\u306b\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3059<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">\u3010\u6cbb\u7642\u3011<\/h3>\n\n\n\n<p>&lt;\u6cbb\u7642\u76ee\u6a19&gt;<\/p>\n\n\n\n<p>\u30fbACT(\u5598\u606f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u30c6\u30b9\u30c8)\u306723\u70b9\u4ee5\u4e0a\u3092\u76ee\u6307\u3059<\/p>\n\n\n\n<p>\u3000\u30fb4\u9031\u9593\u4ee5\u5185\u306b\u5598\u606f\u304c\u3042\u3063\u305f\/\u606f\u5207\u308c\u3057\u305f\/\u65e9\u8d77\u304d\u3057\u305f\/\u5438\u5165\u3092\u4f7f\u3063\u305f\/\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u305f\u304b\u306e\u81ea\u899a<br>\u3000\u3000\u30925\u6bb5\u968e\u3067\u8a55\u4fa1<\/p>\n\n\n\n<p>\u30fb\u30d4\u30fc\u30af\u30d5\u30ed\u30fc\u30e1\u30fc\u30bf\u30fc\u3067\u65e5\u5185\u5909\u52d520%\u4ee5\u5185<\/p>\n\n\n\n<p>&lt;\u6162\u6027\u7ba1\u7406&gt;<\/p>\n\n\n\n<p>1, \u4e2d\u7528\u91cfICS\/LABA\u3092\u958b\u59cb\u3059\u308b<\/p>\n\n\n\n<p>2, \u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u72b6\u614b\u3092\u8a55\u4fa1\u3057\u3066step\u3092\u691c\u8a0e\u3059\u308b<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"621\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-25.png\" alt=\"\" class=\"wp-image-168\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-25.png 600w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-25-290x300.png 290w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p>\u56f3\uff1a\u53c2\u8003\u6587\u732e3\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"748\" height=\"530\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-30.png\" alt=\"\" class=\"wp-image-175\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-30.png 748w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-30-300x213.png 300w\" sizes=\"auto, (max-width: 748px) 100vw, 748px\" \/><\/figure>\n\n\n\n<p>\u56f3\uff1a\u53c2\u8003\u6587\u732e\uff17\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"990\" height=\"459\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-26.png\" alt=\"\" class=\"wp-image-169\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-26.png 990w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-26-300x139.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-26-768x356.png 768w\" sizes=\"auto, (max-width: 990px) 100vw, 990px\" \/><\/figure>\n\n\n\n<p>\u56f3:\u53c2\u8003\u6587\u732e4\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1005\" height=\"339\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-27.png\" alt=\"\" class=\"wp-image-170\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-27.png 1005w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-27-300x101.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-27-768x259.png 768w\" sizes=\"auto, (max-width: 1005px) 100vw, 1005px\" \/><\/figure>\n\n\n\n<p>\u56f3:\u53c2\u8003\u6587\u732e5\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"993\" height=\"508\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-28.png\" alt=\"\" class=\"wp-image-171\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-28.png 993w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-28-300x153.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-28-768x393.png 768w\" sizes=\"auto, (max-width: 993px) 100vw, 993px\" \/><\/figure>\n\n\n\n<p>\u56f3:\u53c2\u8003\u6587\u732e5\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<p>*\u7d4c\u53e3\u30b9\u30c6\u30ed\u30a4\u30c9\u306f1mg\u304b\u3089\u30b9\u30bf\u30fc\u30c8, 5mg\u4ee5\u4e0b\u3092\u76ee\u6307\u3059\u3000\u6700\u592710mg(\u305d\u308c\u4ee5\u4e0a\u306e\u5834\u5408\u306f\u751f\u7269\u5b66\u7684\u88fd\u5264\u3092\u8003\u616e)<\/p>\n\n\n\n<p>\u30fbICS:<\/p>\n\n\n\n<p>\u6297\u708e\u75c7\u85ac<\/p>\n\n\n\n<p>\u526f\u4f5c\u7528:\u53e3\u8154, \u54bd\u982d\u30ab\u30f3\u30b8\u30c0\u75c7\u3084\u55c4\u58f0<\/p>\n\n\n\n<p>\u598a\u5a66\u306b\u3082\u4f7f\u7528\u53ef\u80fd<\/p>\n\n\n\n<p>\u30fbLTRA:<\/p>\n\n\n\n<p>\u6c17\u7ba1\u652f\u62e1\u5f35\u4f5c\u7528\u3068\u6297\u708e\u75c7\u4f5c\u7528\u3092\u6709\u3059\u308b<\/p>\n\n\n\n<p>\u30fb\u6297\u30b3\u30ea\u30f3\u85ac:<\/p>\n\n\n\n<p>\u5598\u606f\u306e\u6c17\u9053\u3067\u306f\u8ff7\u8d70\u795e\u7d4c\u904e\u7dca\u5f35\u72b6\u614b<\/p>\n\n\n\n<p>\u2192\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u306b\u3088\u308b\u6c17\u9053\u53ce\u7e2e\u3084\u7c98\u6db2\u5206\u6ccc\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u6cbb\u7642\u306b\u3064\u306a\u304c\u308b<\/p>\n\n\n\n<p>\u30fb\u751f\u7269\u5b66\u7684\u88fd\u5264<\/p>\n\n\n\n<p>\u7d4c\u53e3\/\u7d4c\u9759\u8108\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u5e74\u306b\uff12\u56de\u4ee5\u4e0a\u4f7f\u7528\u3059\u308b\u5834\u5408\u5c0e\u5165\u3092\u691c\u8a0e\u3059\u308b<\/p>\n\n\n\n<figure class=\"wp-block-table has-small-font-size\"><table class=\"has-fixed-layout\"><tbody><tr><td><\/td><td>\u6297IgE\u6297\u4f53<\/td><td>\u6297IL-5\u6297\u4f53<\/td><td>\u6297IL-5R\u03b1\u6297\u4f53<\/td><td>\u6297IL-4R\u03b1\u6297\u4f53<\/td><td>\u6297TSLP\u6297\u4f53<\/td><\/tr><tr><td>\u4e00\u822c\u540d<\/td><td>\u30aa\u30de\u30ea\u30ba\u30de\u30d6<\/td><td>\u30e1\u30dd\u30ea\u30ba\u30de\u30d6<\/td><td>\u30d9\u30f3\u30e9\u30ea\u30ba\u30de\u30d6<\/td><td>\u30c7\u30e5\u30d4\u30eb\u30de\u30d6<\/td><td>\u30c6\u30bc\u30da\u30eb\u30de\u30d6<\/td><\/tr><tr><td>\u9069\u5fdc\u5e74\u9f62<\/td><td>6\u6b73\u4ee5\u4e0a<\/td><td>6\u6b73\u4ee5\u4e0a<\/td><td>15\u6b73\u4ee5\u4e0a<\/td><td>12\u6b73\u4ee5\u4e0a<\/td><td>12\u6b73\u4ee5\u4e0a<\/td><\/tr><tr><td>\u5bfe\u8c61<\/td><td>\u30a2\u30c8\u30d4\u30fc\u578b\u91cd\u75c7\u5598\u606f\u3067, \u8840\u6e05IgE30-1500IU\/mL<\/td><td>\u91cd\u75c7\u5598\u606f\u3067\u8840\u4e2d\u597d\u9178\u7403150\/\u03bcL\u4ee5\u4e0a<\/td><td>\u91cd\u75c7\u5598\u606f\u3067\u8840\u4e2d\u597d\u9178\u7403150\/\u03bcL\u4ee5\u4e0aor<br>\u904e\u53bb12\u30ab\u6708\u9593\u306b300\/\u03bcL\u4ee5\u4e0a<\/td><td>\u91cd\u75c7\u5598\u606f\u3067\u8840\u4e2d\u597d\u9178\u7403150\/\u03bcL\u4ee5\u4e0aor<br>FeNO25bbp\u4ee5\u4e0a, \u8840\u6e05IgE167IU\/mL\u4ee5\u4e0a<\/td><td>\u91cd\u75c7\u5598\u606f<\/td><\/tr><tr><td>\u5897\u60aa\u6291\u5236\u52b9\u679c<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25ce<\/td><\/tr><tr><td>\u30b9\u30c6\u30ed\u30a4\u30c9\u6e1b\u91cf<\/td><td>\u3007<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25b2<\/td><\/tr><tr><td>\u547c\u5438\u6a5f\u80fd\u6539\u5584<\/td><td>\u3007<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25ce<\/td><td>\u25ce<\/td><\/tr><tr><td>\u4f75\u5b58\u75c7\u3078\u306e\u9069\u5fdc<\/td><td>\u7279\u767a\u6027\u6162\u6027\u8541\u9ebb\u75b9, \u5b63\u7bc0\u6027\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u9f3b\u708e<\/td><td>\u597d\u9178\u7403\u6027\u591a\u767a\u8840\u7ba1\u708e\u6027\u8089\u82bd\u816b<\/td><td><\/td><td>\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e, \u9f3b\u8338\u3092\u4f34\u3046\u6162\u6027\u526f\u9f3b\u8154\u708e<\/td><td><\/td><\/tr><tr><td>\u81ea\u5df1\u6ce8\u5c04<\/td><td>\u3007<\/td><td>\u3007<\/td><td><\/td><td>\u3007<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"666\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-29-1024x666.png\" alt=\"\" class=\"wp-image-172\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-29-1024x666.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-29-300x195.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-29-768x499.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-29.png 1029w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u56f3:\u53c2\u8003\u6587\u732e5\u3088\u308a\u5f15\u7528<\/p>\n\n\n\n<p>\u3010\u53c2\u8003\u6587\u732e\u3011<\/p>\n\n\n\n<p>1, \u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u65e5\u672c\u30a2\u30ec\u30eb\u30ae\u30fc\u5b66\u4f1a\u5598\u606f\u5c02\u9580\u90e8\u4f1a\u6163\u7fd2:\u5598\u606f\u4e88\u9632\u30fb\u7ba1\u7406\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024, \u5354\u548c\u4f01\u753b, \u6771\u4eac, 2024.<br>2, \u91d1\u5b50 \u731b. \u4e2d\u67a2\u6c17\u9053\u7c98\u6db2\u6813\uff0f\u7c98\u6db2\u30b9\u30b3\u30a2. \u7dcf\u5408\u8a3a\u7642. 2025;35(2):147\u2013148. doi:10.11477\/mf.218880510350020147<br>3, \u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb. \u300c\u500b\u5225\u5316\u6cbb\u7642\u76db\u308a\u8fbc\u3093\u3060\u300c\u5598\u606f\u8a3a\u7642\u5b9f\u8df5\u30ac\u30a4\u30c9\u30e9\u30a4\u30f32024\u300d\u306e\u30dd\u30a4\u30f3\u30c8\u306f\uff1f\u300d. \u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb [Internet]. 2024\u5e747\u6708. Available from:<a href=\"https:\/\/medical.nikkeibp.co.jp\/leaf\/mem\/pub\/hotnews\/int\/202407\/585222.html\">https:\/\/medical.nikkeibp.co.jp\/leaf\/mem\/pub\/hotnews\/int\/202407\/585222.html<\/a><br>4, \u6a2a\u6d5c\u52b4\u707d\u75c5\u9662 \u5730\u57df\u9023\u643a\u5ba4. \u5438\u5165\u85ac\u9078\u5b9a\u8868. \u6a2a\u6d5c\u52b4\u707d\u75c5\u9662. [Internet]. [cited 2025 Nov 20]. Available from:chrome-extension:\/\/efaidnbmnnnibpcajpcglclefindmkaj\/https:\/\/yokohamah.johas.go.jp\/data\/media\/yokohama_rosai_medical\/page\/file\/community\/pahrmacy\/drug14.pdf<br>5, <strong>\u4ee5\u4e0b\u306e\u5f62\u5f0f\u3067\u53c2\u8003\u6587\u732e\u306b\u8a18\u8f09\u3067\u304d\u307e\u3059\u3002<\/strong><\/p>\n\n\n\n<p>\u65e5\u672c\u533b\u5e2b\u4f1a. \u6210\u4eba\u6c17\u7ba1\u652f\u5598\u606f\u8a3a\u7642\u306e\u30df\u30cb\u30de\u30e0\u30a8\u30c3\u30bb\u30f3\u30b9. \u65e5\u672c\u533b\u5e2b\u4f1a [Internet]. [cited 2025 Nov 20]. Available from:chrome-extension:\/\/efaidnbmnnnibpcajpcglclefindmkaj\/https:\/\/www.med.or.jp\/dl-med\/chiiki\/allergy\/bronchial_asthma.pdf<br>6, \u539a\u751f\u52b4\u50cd\u79d1\u5b66\u7814\u7a76\u6210\u679c\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9. \u5e73\u621011\u5e74\u5ea6 \u7dcf\u62ec\u30fb\u5206\u62c5\u7814\u7a76\u5831\u544a\u66f8\uff08200001112A0015\uff09. [Internet]. [cited 2025 Nov 20]. Available from:Chrome-extension:\/\/efaidnbmnnnibpcajpcglclefindmkaj\/https:\/\/mhlw-grants.niph.go.jp\/system\/files\/2000\/000156\/200001112A\/200001112A0015.pdf<br>7, \u91d1\u6d25\u30af\u30ea\u30cb\u30c3\u30af. \u305c\u3093\u305d\u304f\u30fbCOPD\u6cbb\u7642\u85ac\u306e\u89e3\u8aac. \u91d1\u6d25\u30af\u30ea\u30cb\u30c3\u30af [Internet]. [cited 2025 Nov 20]. Available from<a href=\"https:\/\/kanadzu-cl.com\/%E3%81%9C%E3%82%93%E3%81%9D%E3%81%8F%E3%83%BBcopd%E6%B2%BB%E7%99%82%E8%96%AC\">https:\/\/kanadzu-cl.com\/%E3%81%9C%E3%82%93%E3%81%9D%E3%81%8F%E3%83%BBcopd%E6%B2%BB%E7%99%82%E8%96%AC<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u75c5\u614b\u3011 \u56f3:\u53c2\u8003\u6587\u732e1\u3088\u308a\u5f15\u7528\u3000\u4e00\u90e8\u6539\u5909 &lt;2\u578b\u708e\u75c7&gt;:Th2\u3084ILC2(2\u578b\u81ea\u7136\u30ea\u30f3\u30d1\u7403)\u304c\u95a2\u4e0e\u3059\u308b\u5598\u606f 1,\u5438\u5165\u611f\u4f5c\u30a2\u30ec\u30eb\u30b2\u30f3\u3092\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8, \u6a39\u72b6\u7d30\u80de\u306a\u3069\u306e\u6297\u539f\u63d0\u793a\u7d30\u80de\u304c\u8caa\u98df\u2192IL-4\u306a\u3069\u306e\u4f5c\u7528\u306b\u3088 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":173,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[30,41],"class_list":["post-162","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-15","tag-30","tag-41"],"_links":{"self":[{"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/posts\/162","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=162"}],"version-history":[{"count":2,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/posts\/162\/revisions"}],"predecessor-version":[{"id":176,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/posts\/162\/revisions\/176"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=\/wp\/v2\/media\/173"}],"wp:attachment":[{"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=162"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=162"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/synapseconferencenet.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=162"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}