{"id":119,"date":"2025-11-13T17:35:17","date_gmt":"2025-11-13T08:35:17","guid":{"rendered":"https:\/\/synapseconferencenet.com\/?p=119"},"modified":"2025-11-13T17:35:17","modified_gmt":"2025-11-13T08:35:17","slug":"%e3%83%98%e3%83%91%e3%83%aa%e3%83%b3","status":"publish","type":"post","link":"https:\/\/synapseconferencenet.com\/?p=119","title":{"rendered":"\u30d8\u30d1\u30ea\u30f3"},"content":{"rendered":"\n<p>\u3010\u6a5f\u5e8f\u3011<\/p>\n\n\n\n<p>&lt;\u51dd\u56fa\u7cfb><\/p>\n\n\n\n<p>\u30fb\u30a2\u30f3\u30c1\u30c8\u30ed\u30f3\u30d3\u30f3(\u4ee5\u4e0bAT)\u306f\u2169a\u56e0\u5b50, \u30c8\u30ed\u30f3\u30d3\u30f3\u3092\u963b\u5bb3\u3057\u6297\u51dd\u56fa\u6d3b\u6027\u3092\u767a\u63ee\u3059\u308b.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"917\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-3-1024x917.png\" alt=\"\" class=\"wp-image-123\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-3-1024x917.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-3-300x269.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-3-768x688.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-3.png 1093w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u5f15\u7528:\u5168\u56fd\u8840\u6db2\u30bb\u30f3\u30bf\u30fc\u5354\u8b70\u4f1a. \u8840\u6db2\u7528\u8a9e\u4e8b\u5178\u300c\u8840\u6f3f\u5206\u753b\u88fd\u5264\u300d. <a href=\"http:\/\/www.ketsukyo.or.jp\/glossary\/ka05.html\">http:\/\/www.ketsukyo.or.jp\/glossary\/ka05.html<\/a>\uff082025\u5e7411\u67088\u65e5\u30a2\u30af\u30bb\u30b9<\/p>\n\n\n\n<p>\u30fb\u30d8\u30d1\u30ea\u30f3\u306f\u30a2\u30f3\u30c1\u30c8\u30ed\u30f3\u30d3\u30f3\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3067, \u30a2\u30f3\u30c1\u30c8\u30ed\u30f3\u30d3\u30f3\u306e\u6297\u51dd\u56fa\u6d3b\u6027\u3092\u6570\u5343\u500d\u306b\u9ad8\u3081\u308b<br>\u2192\u2169a\u56e0\u5b50\u963b\u5bb3\u4f5c\u7528:\u30d8\u30d1\u30ea\u30f3\u304cAT\u306b\u7d50\u5408\u3059\u308b\u306e\u307f\u3067\u4f5c\u7528\u767a\u73fe<br>\u3000\u30c8\u30ed\u30f3\u30d3\u30f3\u963b\u5bb3\u4f5c\u7528:\u30c8\u30ed\u30f3\u30d3\u30f3\u3068AT\u53cc\u65b9\u306b\u30d8\u30d1\u30ea\u30f3\u304c\u7d50\u5408\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"1175\" src=\"http:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/\u753b\u50cf\u306e\u6587\u5b57\u304c\u8aad\u307f\u306b\u304f\u3044\u305f\u3081\u3001\u89e3\u50cf\u5ea6\u3092\u4e0a\u3052-1.png\" alt=\"\" class=\"wp-image-125\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/\u753b\u50cf\u306e\u6587\u5b57\u304c\u8aad\u307f\u306b\u304f\u3044\u305f\u3081\u3001\u89e3\u50cf\u5ea6\u3092\u4e0a\u3052-1.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/\u753b\u50cf\u306e\u6587\u5b57\u304c\u8aad\u307f\u306b\u304f\u3044\u305f\u3081\u3001\u89e3\u50cf\u5ea6\u3092\u4e0a\u3052-1-261x300.png 261w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>Hirsh J, Warkentin TE, Raschke R, et al. <em>Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety<\/em>. Chest. 1998;114(5 Suppl):489S\u2013510S.<br>\u56f32\u300cCatalysis of antithrombin-mediated inactivation of thrombin or factor Xa by UFH or LMWH\u300d\u3088\u308a\u5f15\u7528\u3002ResearchGate\u3088\u308a\u53d6\u5f97\u3002<br><a href=\"https:\/\/www.researchgate.net\/figure\/Catalysis-of-antithrombin-mediated-inactivation-of-thrombin-or-factor-Xa-by-UFH-or-LMWH_fig2_40453331\">https:\/\/www.researchgate.net\/figure\/Catalysis-of-antithrombin-mediated-inactivation-of-thrombin-or-factor-Xa-by-UFH-or-LMWH_fig2_40453331<\/a><\/p>\n\n\n\n<p>&lt;\u305d\u306e\u4ed6\u4f5c\u7528><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"608\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-4-1024x608.png\" alt=\"\" class=\"wp-image-127\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-4-1024x608.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-4-300x178.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-4-768x456.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-4.png 1385w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u3010\u7a2e\u985e\u3011<\/p>\n\n\n\n<p>&lt;\u672a\u5206\u753b\u30d8\u30d1\u30ea\u30f3><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5206\u5b50\u91cf5000-20000\u306e\u30e0\u30b3\u591a\u7cd6<\/li>\n\n\n\n<li>\u534a\u6e1b\u671f:45-60\u5206<\/li>\n<\/ul>\n\n\n\n<p>&lt;\u4f4e\u5206\u5b50\u30d8\u30d1\u30ea\u30f3><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5206\u5b50\u91cf4000-6000\u3068\u672a\u5206\u753b\u30d8\u30d1\u30ea\u30f3\u306b\u6bd4\u3079\u5c0f\u3055\u3044<br>\u2192\u30c8\u30ed\u30f3\u30d3\u30f3\u307e\u3067\u56f2\u3048\u306a\u3044\u305f\u3081, \u2169a\u56e0\u5b50\u963b\u5bb3\u306e\u307f\u884c\u3046<\/li>\n\n\n\n<li>\u30d7\u30ed\u30bf\u30df\u30f3\u3067\u6700\u592760%\u7a0b\u5ea6\u3057\u304b\u56de\u5fa9\u3057\u306a\u3044<\/li>\n\n\n\n<li>\u534a\u6e1b\u671f:2-4\u6642\u9593\u3068\u672a\u5206\u753b\u30d8\u30d1\u30ea\u30f3\u3088\u308a\u9577\u3044<br>*\u6297\u2169a\u4f5c\u7528\u306f\u6295\u4e0e\u5f8c12\u6642\u9593\u3067\u3082\u6301\u7d9a\u3059\u308b<\/li>\n<\/ul>\n\n\n\n<p>&lt;\u30c0\u30ca\u30d1\u30ed\u30a4\u30c9><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4f4e\u5206\u5b50\u91cf(\u5e73\u57476000)\u306e\u3078\u30d1\u30e9\u30f3\u786b\u9178\u3092\u4e3b\u6210\u5206<\/li>\n\n\n\n<li>DIC\u306e\u672c\u90a6\u3067\u306f\u9069\u5fdc<br>*\u6d77\u5916\u3067\u306f\u30d8\u30d1\u30ea\u30f3\u8d77\u56e0\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u767a\u751f\u6642\u306e\u4ee3\u66ff\u85ac\u3068\u3057\u3066\u3082\u4f7f\u7528<\/li>\n\n\n\n<li>\u6297\u7b2c\u2169a\u56e0\u5b50\/\u30c8\u30ed\u30f3\u30d3\u30f3\u6d3b\u6027\u6bd4\u304c\u7d0420:1\u3068\u975e\u5e38\u306b\u9ad8\u3044<\/li>\n\n\n\n<li>\u534a\u6e1b\u671f20\u6642\u9593\u3068\u9577\u3044<\/li>\n<\/ul>\n\n\n\n<p>&lt;\u30d5\u30a9\u30f3\u30c0\u30d1\u30ea\u30cc\u30af\u30b9><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u672a\u5206\u753b\u30d8\u30d1\u30ea\u30f3\u306e\u6700\u5c0f\u6709\u52b9\u5358\u4f4d\u3067\u3042\u308bAT\u7d50\u5408\u90e8\u4f4d\u3092\u5316\u5b66\u5408\u6210\u3057\u305f\u6297\u51dd\u56fa\u85ac<br>\u2192\u7b2c\u2169a\u56e0\u5b50\u963b\u5bb3\u4f5c\u7528\u306e\u307f\u5897\u5f37<\/li>\n\n\n\n<li>\u6295\u4e0e\u5f8c\u7d042\u6642\u9593\u3067\u6700\u9ad8\u8840\u4e2d\u6fc3\u5ea6\u306b\u9054\u3059\u308b<\/li>\n<\/ul>\n\n\n\n<p>\u3010\u7ba1\u7406\u3011<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>APTT1.5-2\u500d\u3067\u7ba1\u7406\u3092\u3059\u308b<\/li>\n\n\n\n<li>APTT\u30921.5\u500d\u306b\u5ef6\u9577\u3059\u308b\u305f\u3081\u306b35000\u5358\u4f4d\/\u65e5\u4ee5\u4e0a\u3092\u8981\u3059\u308b\u3082\u306e\u3092\u30d8\u30d1\u30ea\u30f3\u62b5\u6297\u6027\u3068\u5224\u65ad\u3059\u308b<br>\u539f\u56e0:CRP, \u8840\u6f3f\u30bf\u30f3\u30d1\u30af, \u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u306a\u3069\u306b\u3088\u308b\u30d8\u30d1\u30ea\u30f3\u306e\u4e2d\u548c\u3084AT\u306e\u4f4e\u4e0b<\/li>\n<\/ul>\n\n\n\n<p>\u3010HIT\u3011<\/p>\n\n\n\n<p>&lt;\u6a5f\u5e8f><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"598\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-6-1024x598.png\" alt=\"\" class=\"wp-image-129\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-6-1024x598.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-6-300x175.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-6-768x449.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-6-1536x897.png 1536w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-6.png 1936w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>\u5f15\u7528:\u65e5\u672c\u8840\u6813\u6b62\u8840\u5b66\u4f1a. \u8840\u6813\u6b62\u8840\u5206\u91ce\u306e\u6700\u65b0\u30c8\u30d4\u30c3\u30af\u30b9\uff1a\u30d7\u30ed\u30b3\u30a2\u30b0\u30e9\u30f3\u30c8\u6d3b\u6027\u306b\u5bcc\u3080\u30de\u30a4\u30af\u30ed\u30d1\u30fc\u30c6\u30a3\u30af\u30eb. \u304a\u5f79\u7acb\u3061\u30b7\u30ea\u30fc\u30ba. 2022\u5e748\u6708\u53f7\uff08\u7b2c19\u56de\uff09<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30d8\u30d1\u30ea\u30f3\u3068PF4\u306e\u591a\u5206\u5b50\u8907\u5408\u4f53\u3092\u8a8d\u8b58\u3059\u308bIgG\u30af\u30e9\u30b9\u306e\u8840\u5c0f\u677f\u6d3b\u6027\u5316\u6297\u4f53(\u6297PF4\/\u30d8\u30d1\u30ea\u30f3\u8907\u5408\u4f53\u6297\u4f53:HIT\u6297\u4f53)\u306e\u4e00\u904e\u6027\u7523\u751f\u304c\u539f\u56e0<\/li>\n\n\n\n<li>PF4:\u8840\u5c0f\u677f\u03b1\u9846\u7c92\u4e2d\u306b\u5b58\u5728\u3057, \u8840\u5c0f\u677f\u304c\u6d3b\u6027\u5316\u3055\u308c\u308b\u3068\u653e\u51fa\u3055\u308c, \u8840\u7ba1\u5185\u76ae\u7d30\u80de\u8868\u9762\u3067\u30a2\u30f3\u30c1\u30c8\u30ed\u30f3\u30d3\u30f3\u306b\u7f6e\u63db\u3055\u308c\u308b\u3053\u3068\u3067\u5c40\u6240\u7684\u306b\u8840\u6813\u50be\u5411\u3092\u4fc3\u9032\u3059\u308b.<\/li>\n\n\n\n<li>\u30d8\u30d1\u30ea\u30f3\u306f\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u8868\u9762\u3088\u308aPF4\u3068\u306e\u89aa\u548c\u6027\u304c\u5f37\u3044<br>\u2192\u30d8\u30d1\u30ea\u30f3\u5b58\u5728\u4e0b\u3067\u306f, PF4\u306f\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u304b\u3089\u8840\u4e2d\u306b\u79fb\u52d5\u3057, \u514d\u75ab\u539f\u6027PF4\/\u30d8\u30d1\u30ea\u30f3\u8907\u5408\u4f53\u3092\u5f62\u6210\u3059\u308b.<\/li>\n\n\n\n<li>\u30d8\u30d1\u30ea\u30f3\u3068PF4\u304c1:1-2\u3067\u5b58\u5728\u3059\u308b\u6642, PF4\u306b\u69cb\u9020\u5909\u5316\u304c\u751f\u3058, \u6297\u539f\u6c7a\u5b9a\u57fa\u304c\u9732\u51fa\u3057, marginal zone B cell\u304b\u3089HIT\u6297\u4f53\u304c\u7523\u751f\u3055\u308c\u308b.<\/li>\n<\/ul>\n\n\n\n<p>1, HIT\u6297\u4f53+PF4\/\u30d8\u30d1\u30ea\u30f3\u8907\u5408\u4f53\u306f\u8840\u5c0f\u677f\u819cFc\u03b3R\u2161A\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3057\u8840\u5c0f\u677f\u3092\u6d3b\u6027\u5316\u3055\u305b\u308b<br>\u2192\u8840\u5c0f\u677f\u304b\u3089\u30d7\u30ed\u30b3\u30a2\u30b0\u30e9\u30f3\u30c8\u6d3b\u6027\u306b\u5bcc\u3080\u30de\u30a4\u30af\u30ed\u30d1\u30fc\u30c6\u30a3\u30af\u30eb\u304c\u653e\u51fa\u3055\u308c\u308b<br>*\u30d7\u30ed\u30b3\u30a2\u30b0\u30e9\u30f3\u30c8\u6d3b\u6027\u306b\u5bcc\u3080\u30de\u30a4\u30af\u30ed\u30d1\u30fc\u30c6\u30a3\u30af\u30eb:\u51dd\u56fa\u56e0\u5b50(\u7279\u306b\u7b2c\u2169a\u56e0\u5b50\u3084\u30c8\u30ed\u30f3\u30d3\u30f3)\u306e\u6d3b\u6027\u5316\u3059\u308b\u80fd\u529b\u3092\u6709\u3059\u308b\u819c\u5c0f\u80de<br>\u2192\u30c8\u30ed\u30f3\u30d3\u30f3\u306e\u904e\u5270\u7523\u751f+\u6d88\u8017\u6027\u8840\u5c0f\u677f\u6e1b\u5c11\u3092\u8d77\u3053\u3059<\/p>\n\n\n\n<p>2, HIT\u6297\u4f53+PF4\/\u30d8\u30d1\u30ea\u30f3\u8907\u5408\u4f53\u306f\u5358\u7403\u306eFc\u03b3R\u2161A\u53d7\u5bb9\u4f53\u3084\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u7d44\u7e54\u56e0\u5b50\u306e\u767a\u73fe\u91cf\u3092\u5897\u52a0\u3055\u305b\u308b<br>\u2192\u30c8\u30ed\u30f3\u30d3\u30f3\u306e\u3055\u3089\u306a\u308b\u904e\u5270\u7523\u751f\u3092\u4fc3\u9032\u3059\u308b<\/p>\n\n\n\n<p>3, \u5225\u3067, HIT\u6297\u4f53\u306fThrombomodulin\u4e0a\u3067\u306ePF4\u306b\u3088\u308b\u6d3b\u6027\u5316ProteinC\u7523\u751f\u3092\u6291\u5236\u3059\u308b.<br>\u2192\u30c8\u30ed\u30f3\u30d3\u30f3\u7523\u751f\u3092\u52a9\u9577\u3055\u305b\u308b<br>ProteinC:\u2167a\u3068\u2164a\u5206\u89e3\u3092\u6e1b\u5c11\u3055\u305b, \u30c8\u30ed\u30f3\u30d3\u30f3\u7523\u751f\u3092\u6291\u5236\u3059\u308b<\/p>\n\n\n\n<p>&lt;\u77e5\u8b58><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8840\u6813\u75c7\u3092\u4f34\u3046HIT\u306fHIT-T(HIT with hrombosis)\u3068\u547c\u3070\u308c\u308b<\/li>\n\n\n\n<li>\u597d\u767a\u6642\u671f\u306f\u30d8\u30d1\u30ea\u30f3\u6295\u4e0e\u5f8c5-14\u65e5<\/li>\n\n\n\n<li>\u6b7b\u4ea1\u7387\u306f20%\u306b\u3082\u53ca\u3076<\/li>\n\n\n\n<li>\u672a\u5206\u753b\u30d8\u30d1\u30ea\u30f3\u306b\u3088\u308b\u514d\u75ab\u5b66\u7684\u6e2c\u5b9a\u6cd5\u967d\u6027\u738729.8%\u306b\u5bfe\u3057\u3066\uff0c\u6a5f\u80fd\u7684\u6e2c\u5b9a\u6cd5\u306f9.9%\uff0cHIT\u767a\u75c7\u306f4.8%, HIT-T\u767a\u75c7\u306f3.6%\u3060\u3063\u305f.<br>=HIT\u6297\u4f53\u967d\u6027\u3067\u3042\u3063\u3066\u3082, \u81e8\u5e8a\u7684\u306bHIT, HIT-T\u3092\u8d77\u3053\u3059\u306e\u306f\u3054\u304f\u4e00\u90e8.<br>(\u6c37\u5c71\u306e\u4e00\u89d2\u30e2\u30c7\u30eb)<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1014\" height=\"416\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-5.png\" alt=\"\" class=\"wp-image-128\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-5.png 1014w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-5-300x123.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-5-768x315.png 768w\" sizes=\"auto, (max-width: 1014px) 100vw, 1014px\" \/><\/figure>\n\n\n\n<p>\u5f15\u7528:\u65e5\u672c\u8840\u6813\u6b62\u8840\u5b66\u4f1a. \u8840\u6813\u6b62\u8840\u5206\u91ce\u306e\u6700\u65b0\u30c8\u30d4\u30c3\u30af\u30b9\uff1a\u30d7\u30ed\u30b3\u30a2\u30b0\u30e9\u30f3\u30c8\u6d3b\u6027\u306b\u5bcc\u3080\u30de\u30a4\u30af\u30ed\u30d1\u30fc\u30c6\u30a3\u30af\u30eb. \u304a\u5f79\u7acb\u3061\u30b7\u30ea\u30fc\u30ba. 2022\u5e748\u6708\u53f7\uff08\u7b2c19\u56de\uff09<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>\u767a\u75c7\u30ea\u30b9\u30af<\/td><td>\u672a\u5206\u753b\u30d8\u30d1\u30ea\u30f3<\/td><td>\u4f4e\u5206\u5b50\u30d8\u30d1\u30ea\u30f3<\/td><td>\u30d5\u30a9\u30f3\u30c0\u30d1\u30ea\u30cc\u30af\u30b9<\/td><\/tr><tr><td>\u9ad8\u30ea\u30b9\u30af<br>(1%\u4ee5\u4e0a)<\/td><td>\u5fc3\u81d3\u624b\u8853\u5f8c<br>\u4eba\u5de5\u95a2\u7bc0\u7f6e\u63db\u8853\u5f8c<br>\u53d7\u50b7\u5916\u50b7\u60a3\u8005<br>\u51a0\u52d5\u8108\u75be\u60a3<br>\u8133\u8840\u7ba1\u75be\u60a3<br>\u900f\u6790\u5c0e\u5165\u671f<\/td><td><\/td><td><\/td><\/tr><tr><td>\u4e2d\u30ea\u30b9\u30af<br>(0.1-1%)<\/td><td>\u5185\u79d1\u60a3\u8005<br>\u900f\u6790\u7dad\u6301\u671f<\/td><td>\u5185\u79d1\u60a3\u8005<br>\u91cd\u75c7\u5916\u50b7<br>\u4eba\u5de5\u95a2\u7bc0\u7f6e\u63db\u8853\u5f8c<\/td><td><\/td><\/tr><tr><td>\u4f4e\u30ea\u30b9\u30af<br>(0.1%\u672a\u6e80)<\/td><td>\u7523\u79d1\u60a3\u8005<\/td><td>\u7523\u79d1\u60a3\u8005<\/td><td>\u3059\u3079\u3066\u306e\u60a3\u8005<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>&lt;\u75c7\u72b6><\/p>\n\n\n\n<p>\u25a0\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>HIT\u60a3\u8005\u306e\u7d0495%\u306b\u8a8d\u3081\u308b<\/li>\n\n\n\n<li>\u767a\u75c7\u524d\u306e30-50%\u307e\u3067\u4f4e\u4e0b\u3092\u8a8d\u3081\u308b\u304c, 20&#215;10<sup>3<\/sup>\/\u03bcL\u672a\u6e80\u306e\u9ad8\u5ea6\u306e\u6e1b\u5c11\u306f\u5c11\u306a\u3044.<br>*20&#215;10<sup>3<\/sup>\/\u03bcL\u672a\u6e80\u306b\u306a\u308b\u3068\u81ea\u767a\u6027\u306e\u51fa\u8840\u306e\u53ef\u80fd\u6027\u304c\u51fa\u3066\u304f\u308b<br>\u2192HIT\u3067\u306f\u51fa\u8840\u50be\u5411\u306b\u306a\u308b\u306e\u306f\u7a00<\/li>\n\n\n\n<li>DIC\u306b\u767a\u5c55\u3057\u3046\u308b\u3053\u3068\u3082\u3042\u308b\u305f\u3081\u6ce8\u610f<br>*20&#215;10<sup>3<\/sup>\/\u03bcL\u672a\u6e80, \u8840\u6813\u75c7, \u51fa\u8840\u75c7\u72b6\u3092\u4f34\u3063\u305f\u3089\u6ce8\u610f!!<\/li>\n<\/ul>\n\n\n\n<p>\u25a0\u52d5\u9759\u8108\u8840\u6813\u75c7<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30c8\u30ed\u30f3\u30d3\u30f3\u306e\u904e\u5270\u7523\u751f\u304c\u5f15\u304d\u91d1\u3068\u306a\u308b\u305f\u3081, \u9759\u8108\u8840\u6813\u75c7\u306e\u65b9\u306f\u591a\u3044.<\/li>\n\n\n\n<li>\u8840\u6db2\u900f\u6790\u306a\u3069\u306e\u814e\u4ee3\u66ff\u7642\u6cd5\u3067\u306f, \u8840\u6db2\u56de\u8def\u5185\u306e\u51dd\u56fa\u304cHIT\u3092\u7591\u3046\u6240\u898b\u306e\u4e00\u3064<\/li>\n<\/ul>\n\n\n\n<p>&lt;\u5206\u985e><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"464\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-7-1024x464.png\" alt=\"\" class=\"wp-image-130\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-7-1024x464.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-7-300x136.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-7-768x348.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-7-1536x696.png 1536w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-7.png 1961w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>&lt;\u8a3a\u65ad><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"728\" height=\"1024\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-8-728x1024.png\" alt=\"\" class=\"wp-image-131\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-8-728x1024.png 728w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-8-213x300.png 213w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-8-768x1081.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-8.png 908w\" sizes=\"auto, (max-width: 728px) 100vw, 728px\" \/><\/figure>\n\n\n\n<p>4Ts\u30b9\u30b3\u30a2<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"491\" src=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-9-1024x491.png\" alt=\"\" class=\"wp-image-132\" srcset=\"https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-9-1024x491.png 1024w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-9-300x144.png 300w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-9-768x369.png 768w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-9-1536x737.png 1536w, https:\/\/synapseconferencenet.com\/wp-content\/uploads\/2025\/11\/image-9.png 1588w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>*\u81ea\u7136\u767a\u75c7\u578b\u3067\u306f\u30b9\u30b3\u30a2\u304c\u904e\u5c0f\u8a55\u4fa1\u3055\u308c\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981<\/p>\n\n\n\n<p>\u5f15\u7528:\u65e5\u672c\u8840\u6813\u6b62\u8840\u5b66\u4f1a. \u8840\u6813\u6b62\u8840\u5206\u91ce\u306e\u6700\u65b0\u30c8\u30d4\u30c3\u30af\u30b9\uff1a\u30d7\u30ed\u30b3\u30a2\u30b0\u30e9\u30f3\u30c8\u6d3b\u6027\u306b\u5bcc\u3080\u30de\u30a4\u30af\u30ed\u30d1\u30fc\u30c6\u30a3\u30af\u30eb. \u304a\u5f79\u7acb\u3061\u30b7\u30ea\u30fc\u30ba. 2022\u5e748\u6708\u53f7\uff08\u7b2c19\u56de\uff09<\/p>\n\n\n\n<p>&lt;\u6cbb\u7642><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u30d8\u30d1\u30ea\u30f3\u306e\u4e2d\u6b62<br>+\u30a2\u30eb\u30ac\u30c8\u30ed\u30d0\u30f3\u6295\u4e0e, 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https:\/\/www.jspc.gr.jp\/Contents\/public\/pdf\/shi-guide07_08.pdf<\/li>\n\n\n\n<li>\u68ee\u4e0b\u82f1\u7406\u5b50. \u51fa\u8840\u50be\u5411\u306e\u9451\u5225\u8a3a\u65ad. \u65e5\u672c\u5185\u79d1\u5b66\u4f1a\u96d1\u8a8c. 2020;109(7):1340\u20131346<\/li>\n\n\n\n<li>\u65e5\u672c\u8840\u6813\u6b62\u8840\u5b66\u4f1a. \u8840\u6813\u6b62\u8840\u5206\u91ce\u306e\u6700\u65b0\u30c8\u30d4\u30c3\u30af\u30b9\uff1a\u30d7\u30ed\u30b3\u30a2\u30b0\u30e9\u30f3\u30c8\u6d3b\u6027\u306b\u5bcc\u3080\u30de\u30a4\u30af\u30ed\u30d1\u30fc\u30c6\u30a3\u30af\u30eb. \u304a\u5f79\u7acb\u3061\u30b7\u30ea\u30fc\u30ba. 2022\u5e748\u6708\u53f7\uff08\u7b2c19\u56de\uff09<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u3010\u6a5f\u5e8f\u3011 &lt;\u51dd\u56fa\u7cfb> \u30fb\u30a2\u30f3\u30c1\u30c8\u30ed\u30f3\u30d3\u30f3(\u4ee5\u4e0bAT)\u306f\u2169a\u56e0\u5b50, \u30c8\u30ed\u30f3\u30d3\u30f3\u3092\u963b\u5bb3\u3057\u6297\u51dd\u56fa\u6d3b\u6027\u3092\u767a\u63ee\u3059\u308b. 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